A discussion of egoism and altruism as related both to ethical theory and moral psychology. Williams considers and rejects various arguments for and against the existence of egoistic motives and the rationality of someone motivated by self-interest. He ultimately attempts to give a more Humean defense of altruism, as opposed to the more Kantian defenses found in Thomas Nagel, for example.

Anderson and Csima :245–264, 2014) defined a jump operator, the bounded jump, with respect to bounded Turing reducibility. They showed that the bounded jump is closely related to the Ershov hierarchy and that it satisfies an analogue of Shoenfield jump inversion. We show that there are high bounded low sets and low bounded high sets. Thus, the information coded in the bounded jump is quite different from that of the standard jump. We also consider whether the analogue of the Jump (...) Theorem holds for the bounded jump: do we have A≤bTB\documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$$A \le _{bT}B$$\end{document} if and only if Ab≤1Bb\documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$$A^b \le _1 B^b$$\end{document}? We show the forward direction holds but not the reverse. (shrink)

Let $D_{tt} $ denote the set of truth-table degrees. A bijection π: $D_{tt} \to \,D_{tt} $ is an automorphism if for all truth-table degrees x and y we have $ \leqslant _{tt} \,y\, \Leftrightarrow \,\pi (x)\, \leqslant _{tt} \,\pi (y)$ . We say an automorphism π is fixed on a cone if there is a degree b such that for all $x \geqslant _{tt} b$ we have π(x) = x. We first prove that for every 2-generic real X we have (...) X' $X' \le _{tt} \,X\, \oplus \,0'$ . We next prove that for every real $X \ge _{tt} \,0'$ there is a real Y such that $Y \oplus 0{\text{'}}\, \equiv _{tt} \,Y{\text{'}} \equiv _{tt} \,X$ . Finally, we use this to demonstrate that every automorphism of the truth-table degrees is fixed on a cone. (shrink)

A real X is defined to be relatively c.e. if there is a real Y such that X is c.e.(Y) and \documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$${X \not\leq_T Y}$$\end{document}. A real X is relatively simple and above if there is a real Y (...) nonempty \documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$${\Pi^0_1}$$\end{document} class contains a member which is not relatively c.e. and that every 1-generic real is relatively simple and above. (shrink)

We show that a version of Ramsey’s theorem for trees for arbitrary exponents is equivalent to the subsystem ${{\sf ACA}^\prime_{0}}$ of reverse mathematics.

Compared to approach motivation, avoidance motivation evokes vigilance, attention to detail, systematic information processing, and the recruitment of cognitive resources. From a conservation of energy perspective it follows that people would be reluctant to engage in the kind of effortful cognitive processing evoked by avoidance motivation, unless the benefits of expending this energy outweigh the costs. We put forward three empirically testable propositions concerning approach and avoidance motivation, investment of energy, and the consequences of such investments. Specifically, we propose that (...) compared to approach-motivated people, avoidance-motivated people (a) carefully select situations in which they exert such cognitive effort, (b) only perform well in the absence of distracters that occupy cognitive resources, and (c) become depleted after exerting such cognitive effort. (shrink)

I present the arguments of Gabriel Marcel which are intended to overcome the potentially negative impact of technology on the human. Marcel is concerned with forgetting or rejecting human nature. His perspective is metaphysical. He is concerned with the attitude of the "mere technician" who is so immersed in technology that the values which promote him as an authentic person with human dignity are discredited, omitted, denied, minimized, overshadowed, or displaced. He reviews the various losses in ontological values which curtail (...) the full realization of the human person in his dignity. The impact of technology leads too often to a loss of the sense of the mystery of being and self, authenticity and integrity, the concrete and the existential, truth and dialogue, freedom and lover, humanity and community, fidelity and creativity, the natural and the transcendent, commitment and virtue, respect of the self and responsiveness to others, and especially of the spiritual and the sacred. Thus, the task of the philosopher is to be a watchman, un veilleur, on the alert for a hopeful resolution of the human predicament. (shrink)

We say that a real X is n-generic relative to a perfect tree T if X is a path through T and for all $\Sigma _{n}^{0}(T)$ sets S, there exists a number k such that either X|k ∈ S or for all σ ∈ T extending X|k we have σ ∉ S. A real X is n-generic relative to some perfect tree if there exists such a T. We first show that for every number n all but countably many reals (...) are n-generic relative to some perfect tree. Second, we show that proving this statement requires ZFC− + "∃ infinitely many iterates of the power set of ω". Third, we prove that every finite iterate of the hyperjump. ${\cal O}^{(n)}$ , is not 2-generic relative to any perfect tree and for every ordinal α below the least λ such that supβ<i (βth admissible) = λ, the iterated hyperjump ${\cal O}^{(\alpha)}$ is not 5-generic relative to any perfect tree. Finally, we demonstrate some necessary conditions for reals to be 1-generic relative to some perfect tree. (shrink)

Individuals regaining reliable day-to-day walking function after incomplete spinal cord injury report persisting unsteadiness when confronted with walking challenges. However, quantifiable measures of walking capacity lack the sensitivity to reveal underlying impairments of supra-spinal locomotor control. This study investigates the relationship between intramuscular coherence and corticospinal dynamic balance control during a visually guided Target walking treadmill task. In thirteen individuals with iSCI and 24 controls, intramuscular coherence and cumulant densities were estimated from pairs of Tibialis anterior surface EMG recordings during (...) normal treadmill walking and a Target walking task. The approximate center of mass was calculated from pelvis markers. Spearman rank correlations were performed to evaluate the relationship between intramuscular coherence, clinical parameters, and center of mass parameters. In controls, we found that the Target walking task results in increased high-frequency intramuscular coherence, which negatively related to changes in the center of mass movement, whereas this modulation was largely reduced in individuals with iSCI. The impaired modulation of high-frequency intramuscular coherence during the Target walking task correlated with neurophysiological and functional readouts, such as motor-evoked potential amplitude and outdoor mobility score, as well as center of mass trajectory length. The Target walking effect, the difference between Target and Normal walking intramuscular coherence, was significantly higher in controls than in individuals with iSCI [F = 13.042, p < 0.001]. Intramuscular coherence obtained during challenging walking in individuals with iSCI may provide information on corticospinal gait control. The relationships between biomechanics, clinical scores, and neurophysiology suggest that intramuscular coherence assessed during challenging tasks may be meaningful for understanding impaired supra-spinal control in individuals with iSCI. (shrink)

We show that a version of Ramsey’s theorem for trees for arbitrary exponents is equivalent to the subsystem \documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$${{\sf ACA}^\prime_{0}}$$\end{document} of reverse mathematics.

A very readable, scholarly, and provocative book by Louis Dupré gives a new interpretation and meaning to the passage to modernity. Dupre gives a fascinating hermeneutic analysis of the creative revolution achieved by the early and late humanists and thinkers of the Renaissance in rethinking reality in terms beyond the ancient and medieval ontotheological synthesis of God, the human, and the Cosmos. The book analyzes how the break leading into modernity took place at that time and prior to the second (...) modern revolution--the Enlightenment, when the transcendent component was disowned in favor of the human subject. Later, both were deprioritized in favor of the cosmos. (shrink)

Volume 20, Issue 8, August 2020, Page W12-W13.

Inborn errors of vitamin B12 (cobalamin) metabolism are associated with homocystinuria and methylmalonic aciduria, either alone or in combination. A number of these disorders have provided the first evidence for the existence of important steps in the transport or metabolism of cobalamin in eukaryotic cells. Eight complementation classes have been defined on the basis of somatic cell hybridization studies. Although the majority of patients present in infancy or early childhood, some are not diagnosed until adolescence or later. For some of (...) these disorders, prenatal diagnosis and therapy with cobalamin during pregnancy has been attempted. Although only males have been described with cblE disease, all of these disorders are presumed to be autosomal recessive in inheritance. The clinical and laboratory aspects of the different complementation classes (cblA–cblG) are reviewed here. (shrink)

By examining the shared neuro-cognitive correlates of curiosity and creativity, we better understand the brain basis of creativity. However, by only examining shared components, important neuro-cognitive correlates are overlooked. Here, we argue that any comprehensive brain model of creativity should consider multiple cognitive processes and, alongside the interplay between brain networks, also the neurochemistry and neural oscillations that underly creativity.

Spontaneous eye blink rate has been linked to attention and memory, specifically working memory. sEBR is also related to striatal dopamine activity with schizophrenia and Parkinson’s disease showing increases and decreases, respectively, in sEBR. A weakness of past studies of sEBR and WM is that correlations have been reported using blink rates taken at baseline either before or after performance of the tasks used to assess WM. The goal of the present study was to understand how fluctuations in sEBR during (...) different phases of a visual WM task predict task accuracy. In two experiments, with recordings of sEBR collected inside and outside of a magnetic resonance imaging bore, we observed sEBR to be positively correlated with WM task accuracy during the WM delay period. We also found task-related modulation of sEBR, including higher sEBR during the delay period compared to rest, and lower sEBR during task phases that place demands on visual attention. These results provide further evidence that sEBR could be an important predictor of WM task performance with the changes during the delay period suggesting a role in WM maintenance. The relationship of sEBR to DA activity and WM maintenance is discussed. (shrink)

In this systematic introduction to the philosophy of Charles S. Peirce, the author focuses on four of Peirce's fundamental conceptions: pragmatism and Peirce's development of it into what he called 'pragmaticism'; his theory of signs; his phenomenology; and his theory that continuity is of prime importance for philosophy. He argues that at the centre of Peirce's philosophical project is a unique form of metaphysical realism, whereby continuity and evolutionary change are both necessary for our understanding of experience. In his final (...) chapter Professor Hausman applies this version of realism to contemporary controversies between anti-realists and anti-idealists. Peirce's views are compared to those of such contemporary figures as Davidson, Putnam, and Rorty. The book will be of particular interest to philosophers concerned with American philosophy and current debates on realism as well as linguists working in semiotics. (shrink)